A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Quality Control of 244205-40-1.
Koszelewski, Dominik;Paprocki, Daniel;Brodzka, Anna;Keciek, Aleksandra;Wilk, Monika;Ostaszewski, Ryszard research published 《 The sustainable copper-catalyzed direct formation of highly functionalized p-quinols in water》, the research content is summarized as follows. The straightforward copper-catalyzed formation of p-quinols in water under air has been accomplished employing arylboronic acids. Various substituted p-benzoquinol derivatives of biol. importance were obtained in good yield. Furthermore, the synthesis of target p-quinols under physiol. conditions in serum and carbonate buffer is demonstrated. The essential features of this method are the high functional group tolerance and scalable one-pot preparation of p-quinols from corresponding arylboronic acid. Very mild reaction conditions, an absence of the heavy toxic metals, simple procedure as well as high chemoselectivity makes the established protocol desirable for academia and pharmaceutical industry laboratories
244205-40-1, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., Quality Control of 244205-40-1
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary