Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Product Details of C7H6Br2.
Hu, Chao;Farshadfar, Kaveh;Dietl, Martin C.;Cervantes-Reyes, Alejandro;Wang, Tao;Adak, Tapas;Rudolph, Matthias;Rominger, Frank;Li, Jun;Ariafard, Alireza;Hashmi, A. Stephen K. research published ã?Gold-Catalyzed [5,5]-Rearrangementã? the research content is summarized as follows. A highly efficient gold-catalyzed cycloisomerization of 1,5-diynes to afford indeno[1,2-c]furans I [R = n-pentyl, Ph, 4-ClC6H4, etc.; R1 = H, 6-OMe 5-F, etc.; R2 = 4-MeC6H4, 2-IC6H4CH2, 3-I-4-MeC6H3, etc.] was developed. Various functional groups were tolerated under the mild reaction conditions, which provided an alternative approach for the synthesis of compounds I. On the basis of mechanistic studies, including crossover experiments, deuterium labeling and computational chem., the product formation proceeded via a formal [5,5]-sigmatropic rearrangement, a yet unknown reactivity pattern in gold catalysis. Instead of a synchronous concerted [5,5]-sigmatropic rearrangement and beyond an asynchronous concerted mode, each involving a single transition state, two energetically low transition states (1.8 and 5.6 kJ/mol) and an intermediate associate of the migrating benzyl cation and the vinyl gold species could be located in the computations.
823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.
3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.
3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., Product Details of C7H6Br2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary