Organic compounds having carbon bonded to bromine are called organic bromides. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Safety of 6-Bromohexanoic acid.
Hou, Zhanfeng;Wang, Yuena;Wan, Chuan;Song, Lijuan;Wang, Rui;Guo, Xiaochun;Yang, Dongyan;Zhang, Yaping;Qin, Xuan;Zhou, Ziyuan;Zhang, Xinhao;Yin, Feng;Li, Zigang research published ã?Sulfonium Triggered Alkyne-Azide Click Cycloadditionã? the research content is summarized as follows. Herein the first facile Cu-free click reaction between alkynyl sulfoniums RCCR1 (R = diphenyl-sulfanyliumyl, dibenzothiophenium-5-yl, thianthrenium-5-yl, etc.; R1 = H, Me, Ph, etc.) and azides R2N3 [R2 = C6H5CH2, CH2CO2H, Ph(CH2)3, etc.] at ambient temperatures in aqueous media was reported. DFT computations indicate that the sulfonium group is the key factor to gaining reactivity by stabilizing LUMO+1 and influencing the charge distribution of the triple bond. Sulfonium alkynes can be easily synthesized and scaled up, and most of them are biocompatible. Here candidate mols. were prepared and tested their use in multiple proof-of-concept biol. applications.
Safety of 6-Bromohexanoic acid, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary