Organic compounds having carbon bonded to bromine are called organic bromides. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application of C6H6BBrO2.
Hong, Seung Youn;Radosevich, Alexander T. research published ã?Chemoselective Primary Amination of Aryl Boronic Acids by PIII/PV=O-Catalysis: Synthetic Capture of the Transient Nef Intermediate HNOã? the research content is summarized as follows. A catalytic approach to intercept the transient HNO for a chemoselective primary amination of arylboronic acids was reported. A phosphetane-based catalyst operating within PIII/PV=O redox cycling was shown to capture HNO, generated in situ by Nef decomposition of 2-nitropropane, to selectively install the primary amino group at aryl Csp2 centers. The method furnished versatile primary arylamines from arylboronic acid substrates with the preservation of otherwise reactive functional groups.
Application of C6H6BBrO2, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary