Hezarcheshmeh, Nasrin Karami team published research in Molecular Diversity in 2022 | 70-23-5

Electric Literature of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Electric Literature of 70-23-5.

Hezarcheshmeh, Nasrin Karami;Azizian, Javad research published 《 Solvent-free synthesis of new spiropyrroloindole compounds using Fe3O4/TiO2/MWCNTs MNCs via multicomponent reactions: assessment of new spiropyrroloindole antioxidant activity》, the research content is summarized as follows. In this study, water extract of Spinacia oleracea leaves was used for the synthesis of Fe3O4/TiO2/MWCNTs magnetic nanocomposites and high performance of this catalyst was confirmed by employing it in the solvent-free multicomponent reactions of anilines RC6H4NH2 (R = Me, OMe, NO2), oxalyl chloride, ethane-1,2-diamine or hydroxyethylamine, electron-deficient acetylenic esters R1OC(O)CCC(O)OR1 (R1 = Me, Et), α-haloketones R2C(O)CH2Br (R2 = ethoxycarbonyl, 4-methylphenyl, 4-methoxyphenyl, 4-bromophenyl) and Et3N at room temperature for the generation of new spiropyrroloindoles I (R3 = O, NH) in high yields. This catalyst could be utilized several times and has a significant role in the yield of products I. The synthesized spiropyrroloindoles I have NH and OH group in their structure and for this reason, they have good antioxidant activity. Also, by employing Gram-pos. and Gram-neg. bacteria, the disk diffusion procedure confirmed the antimicrobial effect of some spiropyrroloindole derivatives I. The results showed that synthesized spiropyrroloindoles I prevented the bacterial growth. This used process for preparation of new spiropyrroloindoles I has some improvements such as low reaction time, product with high yields, and simple separation of catalyst and products.

Electric Literature of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary