A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Synthetic Route of 90-59-5.
El-Attar, Mona;Aazam, Elham research published 《 Redox behavior, spectroscopic investigations, theoretical interpretation and biological effectiveness of some novel prepared bis-azomethine derivatives and their copper(II) complexes》, the research content is summarized as follows. Three new bis-azomethine derivatives were synthesized in a good yield, along with their copper(II) complexes and confirmed by IR, 13C-NMR, 1H-NMR, MS, ESR, powder XRD and UV-visible spectroscopy. The spectral studies indicated that the ligands in all complexes act as dibasic tetradentate, coordinated through two azomethine nitrogen and two deprotonated phenolic oxygen atoms. Square planar geometries were assigned for Cu(II) complexes in monomeric structures. Also, quantum chem. calculations using DFT were conducted to elucidate the effect of quantum chem. parameters on the mol. and electronic structures of the mols. under consideration, and then confirming their electrochem. behavior and biol. effectiveness. There were good correlations between practical and theor. studies. The redox pathway of bis-azomethine derivatives and their Cu(II) complexes was elucidated and confirmed based on exptl. and theor. calculations In vitro antimicrobial effectiveness of the synthesized three ligands and their Cu(II) complexes exhibited varying degrees of inhibitory effect on the growth of the test pathogenic microorganisms, confirming that antimicrobial efficiency is dependent on the mol. structure of the prepared compounds and their liposoly. The MIC was also determined for the compound H2Lc which exhibited the highest antimicrobial activity against each of Pseudomonas aeruginosa (G-) and Candida albicans.
Synthetic Route of 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.
3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.
3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).
3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., 90-59-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary