A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 20469-65-2, formula is C8H9BrO2, Name is 1-Bromo-3,5-dimethoxybenzene. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Computed Properties of 20469-65-2.
Duan, Wenwen;Sun, Ying;Wu, Meng;Zhang, Zhiyuan;Zhang, Taotao;Wang, Huan;Li, Fei;Yang, Lingyun;Xu, Yueming;Liu, Zhi-Jie;Hua, Tian;Nie, Hong;Cheng, Jianjun research published 《 Carbon-silicon switch led to the discovery of novel synthetic cannabinoids with therapeutic effects in a mouse model of multiple sclerosis》, the research content is summarized as follows. Designed and synthesized a variety of novel cannabinoids based on the structural backbones of THC and CBD using the carbon-silicon switch strategy. A di-Me silyl group were introduced as the tail group and two series of novel compounds were designed and synthesized, which showed a wide range of binding affinity for CB1 and CB2 receptors. Among them, compound I were identified as a non-selective CB1 and CB2 agonist and II as a selective agonist for the CB2 receptor. Preliminary screening showed that both compounds I and II was improved metabolic stability than their carbon analogs and good in-vivo pharmacokinetic profiles. Furthermore, both I and II significantly alleviated the phenotype of exptl. autoimmune encephalomyelitis (EAE) in mice.
Computed Properties of 20469-65-2, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., 20469-65-2.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary