Zhang, Kezhuo; Huang, Jiaxin; Zhao, Wanxiang published an article in 2022. The article was titled 《Rh-Catalyzed Coupling of Aldehydes with Allylboronates Enables Facile Access to Ketones》, and you may find the article in Chemistry – A European Journal.SDS of cas: 14660-52-7 The information in the text is summarized as follows:
A novel strategy for the preparation of ketones R1C(O)CHR2CH2CH2R3 (R1 = n-pentyl, cyclohexyl, Ph, 2-thienyl, 4-pyridinyl, etc., R2 = R3 = H; R1 = Ph, R2 = Ph, 4-MeC6H4, 2-naphthyl, 3-furyl, etc., R3 = H; R1 = Ph, R2 = H, R3 = Et, Ph; etc.) from aldehydes R1CHO and allylic boronic esters R2CH:CHCHR3Bpin is presented. This reaction involves the allylation of aldehydes with allylic boronic esters and the Rh-catalyzed chain-walking of homoallylic alcs. The key to this successful development is the protodeboronation of alkenyl boryl ether intermediate via a tetravalent borate anion species in the presence of KHF2 and MeOH. This approach features mild reaction conditions, broad substrate scope, and excellent functional group tolerance. Mechanistic studies also supported that the tandem allylation and chain-walking process are involved.Ethyl 5-bromovalerate(cas: 14660-52-7SDS of cas: 14660-52-7) was used in this study.
Ethyl 5-bromovalerate(cas: 14660-52-7) belongs to bromides. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents.SDS of cas: 14660-52-7
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary