SDS of cas: 76006-33-2In 2018 ,《Regioselective C-H Alkylation via Carboxylate-Directed Hydroarylation in Water》 appeared in Chemistry – A European Journal. The author of the article were Zhang, Guodong; Jia, Fan; Goossen, Lukas J.. The article conveys some information:
In the presence of catalytic [RuCl2(p-cym)]2 and using Li3PO4 as the base, benzoic acids react with olefins in water to afford the corresponding 2-alkylbenzoic acids in moderate to excellent yields. This C-H alkylation process is generally applicable to diversely substituted electron-rich and electron-deficient benzoic acids, along with α,β-unsaturated olefins including unprotected acrylic acid. The widely available carboxylate directing group can be removed or used for further derivatization. Mechanistic studies revealed that the transformation proceeds via a ruthenacycle intermediate. In the experiment, the researchers used 3-Bromo-2-methylbenzoic acid(cas: 76006-33-2SDS of cas: 76006-33-2)
3-Bromo-2-methylbenzoic acid(cas: 76006-33-2) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Due to the reactivity of bromide, they are used as potential precursors or important intermediates in organic synthesis. SDS of cas: 76006-33-2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary