The author of 《Asymmetric α-alkylation of cyclic β-keto esters and β-keto amides by phase-transfer catalysis》 were Wang, Yakun; Li, Yueyun; Lian, Mingming; Zhang, Jixia; Liu, Zhaomin; Tang, Xiaofei; Yin, Hang; Meng, Qingwei. And the article was published in Organic & Biomolecular Chemistry in 2019. COA of Formula: C4H7BrO2 The author mentioned the following in the article:
Without employing any transition metal, a highly enantioselective α-alkylation of cyclic β-keto esters and β-keto amides has been realized by phase-transfer catalysis. This improved procedure is applicable to different kinds of bromides with cinchona derivatives and gives the corresponding products e.g., I and e.g., II, in excellent enantiopurities (up to 98% ee) and good yields (up to 98%). Moreover, the reaction was scalable and the phase-transfer catalyst was recyclable. This provided an alternative and competitive method to the asym. α-alkylation of β-dicarbonyl compounds The experimental process involved the reaction of Methyl 3-bromopropanoate(cas: 3395-91-3COA of Formula: C4H7BrO2)
Methyl 3-bromopropanoate(cas: 3395-91-3) belongs to bromides. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact.COA of Formula: C4H7BrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary