Wang, Guowei; Jiang, Timing; Li, Sen; Hou, Huijie; Xiao, Keke; Hu, Jingping; Liang, Sha; Liu, Bingchuan; Yang, Jiakuan published an article in 2021. The article was titled 《Occurrence and exposure risk evaluation of polyhalogenated carbazoles (PHCZs) in drinking water》, and you may find the article in Science of the Total Environment.Related Products of 6825-20-3 The information in the text is summarized as follows:
Although polyhalogenated carbazoles (PHCZs) can be generated and detected in drinking water, their occurrence and potential health risks to humans via drinking water ingestion are not well known. In this study, 11 PHCZs were screened in drinking water samples from Wuhan, the most populous city in central China. The total concentration of PHCZs could be up to 53.48 ng/L with a median level of 8.19 ng/L, which was comparable to polychlorinated biphenyls and poly- and perfluoroalkyl substances reported in the literatures for drinking water. Composition profiles revealed that 3,6-dichlorocarbazole, 3-chlorocarbazole, 3-bromocarbazole and 3,6-dibromocarbazole were the predominant PHCZ congeners in the tested samples. Regional differences in the levels and patterns of PHCZs suggested that anthropogenic releases should be the dominant source compared to natural generation. Potential health risks associated to the levels of PHCZs in drinking water were assessed using the toxic equivalent (TEQs) method. The estimated daily intake of PHCZs via drinking water ingestion is up to 0.38 pg-TEQ/kg body weight/day for infants, nearly 4.5 times higher than that for adults, and appears to reach the maximum permissible concentration set by certain authority agencies. Overall, drinking water ingestion represents an important exposure pathway for PHCZs. This is the first comprehensive study on the abundance and health risks of PHCZs in drinking water. In the experiment, the researchers used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Related Products of 6825-20-3)
3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Related Products of 6825-20-3
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary