Sterman, Andrej; Kosmrlj, Janez; Zigart, Nina; Gobec, Stanislav; Sosic, Izidor; Casar, Zdenko published their research in Advanced Synthesis & Catalysis in 2021. The article was titled 《Catalytic Approach to Diverse α-Aminoboronic Acid Derivatives by Iridium-Catalyzed Hydrogenation of Trifluoroborate-Iminiums》.Safety of 5-Bromobenzo[d][1,3]dioxole The article contains the following contents:
Structurally diverse benzyl protected trifluoroborate-ammoniums were prepared in good to high yields by an efficient hydrogenation of corresponding trifluoroborate-iminiums using Crabtree’s catalyst. Subsequent N- and B-deprotections were demonstrated on selected examples to provide several α-aminoboronic acids. Preliminary experiments on asym. version of the reaction indicated a correlation between E/Z-ratio in the trifluoroborate-iminium substrate and enantioselectivity. The broad scope, operational simplicity and efficiency of the presented method imply its high potential for a facile access to libraries of α-aminoboronic acid derivatives that can be used in medicinal chem. applications and beyond. In addition to this study using 5-Bromobenzo[d][1,3]dioxole, there are many other studies that have used 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Safety of 5-Bromobenzo[d][1,3]dioxole) was used in this study.
Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Safety of 5-Bromobenzo[d][1,3]dioxole
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary