《Oxidation of Substituted Toluenes by Nitric Acid》 was written by Kazakov, P. V.; Gorelenko, S. V.; Derevyagina, I. D.; Lukashov, O. I.; Mirzabekova, N. S.. Electric Literature of C7H5BrO2This research focused ontoluene nitric acid oxidation; benzoic acid preparation. The article conveys some information:
Oxidation by HNO3 at atm. pressure of toluenes with electroneg. substituents on the benzene ring was studied. A method enabling the corresponding benzoic acids to be obtained in high yields with minimal wastes was developed. The method could be used in the laboratory and in production of medicines. The results came from multiple reactions, including the reaction of 4-Bromobenzoic acid(cas: 586-76-5Electric Literature of C7H5BrO2)
4-Bromobenzoic acid(cas: 586-76-5) has been used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography. It was used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.Electric Literature of C7H5BrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary