Hasegawa, Yoko; Cantin, Thomas; Decaens, Jonathan; Couve-Bonnaire, Samuel; Charette, Andre B.; Poisson, Thomas; Jubault, Philippe published an article in 2022. The article was titled 《Catalytic Asymmetric Syntheses of Alkylidenecyclopropanes from Allenoates with Donor-Acceptor and Diacceptor Diazo Reagents》, and you may find the article in Chemistry – A European Journal.Safety of Benzyl 2-bromoacetate The information in the text is summarized as follows:
The first diastereo- and enantioselective cyclopropanation reactions of electron-deficient allenes with donor-acceptor and diacceptor diazo reagents was described. The desired enantioenriched alkylidenecyclopropanes (ACPs) were obtained in high yields with high diastereo- and enantioselectivities in the presence of Rh2((S)-TCPTAD)4 or Rh2((R)-BTPCP)4 catalysts (up to 95% yield, >95 : 5 d.r. and 99 : 1 e.r.). This methodol. gave a direct access to ACPs bearing multiple electron-deficient substituents and allows to further expand the availability of ACPs chem. Interestingly, during the examination of the scope of this reaction, the asym. intramol. C-H insertion reaction into tert-Bu group was observed as a side reaction with up to 94 : 6 e.r. In the experimental materials used by the author, we found Benzyl 2-bromoacetate(cas: 5437-45-6Safety of Benzyl 2-bromoacetate)
Benzyl 2-bromoacetate(cas: 5437-45-6) belongs to benzyl acetate. Benzyl acetate is a synthetic chemical produced for industry from benzyl alcohol and acetic acid, but is also naturally present in the essential oils of many plants, including jasmine and ylang ylang.Safety of Benzyl 2-bromoacetate
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary