In 2022,Zhu, Jin; Wang, Yidong; Charlack, Aaron D.; Wang, Yi-Ming published an article in Journal of the American Chemical Society. The title of the article was 《Enantioselective and Diastereodivergent Allylation of Propargylic C-H Bonds》.Product Details of 2635-13-4 The author mentioned the following in the article:
An iridium-catalyzed stereoselective coupling of allylic ethers and alkynes to generate 3,4-substituted 1,5-enynes was reported. Under optimized conditions, the coupling products were formed with excellent regio-, diastereo-, and enantioselectivities, and the protocol was functional group tolerant. Moreover, conditions that allowed the reaction to proceed with complete reversal of diastereoselectivity was reported. Mechanistic studies were consistent with an unprecedented dual role for the iridium catalyst, enabling the propargylic deprotonation of the alkyne through π-coordination, as well as the generation of a π-allyl species from the allylic ether starting material. The experimental part of the paper was very detailed, including the reaction process of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Product Details of 2635-13-4)
Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Product Details of 2635-13-4
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary