Zeng, Liang; Fu, Hua; Qiao, Renzhong; Jiang, Yuyang; Zhao, Yufen published the artcile< Efficient copper-catalyzed synthesis of N-(alkyl)anthranilic acids via an ortho-substituent effect of the carboxyl group of 2-halobenzoic acids at room temperature>, Related Products of 16426-64-5, the main research area is anthranilic acid alkyl preparation copper iodide BINOL; Ullmann reaction amine halobenzoic acid amination copper BINOL.
A method for the synthesis of the title compounds [i.e., 2-(aminoalkyl)benzoic acid derivatives, N-(alkyl)anthranilic acids] is reported here. The protocol uses inexpensive copper iodide/racemic 1,1′-binaphthyl-2,2′-diol (racemic-BINOL) as catalyst/ligand system, readily available 2-halobenzoic acids and aliphatic amines as starting materials. The coupling reactions were performed at room temperature, and various functionalities in the substrates were tolerated.
Advanced Synthesis & Catalysis published new progress about Alicyclic amines Role: RCT (Reactant), RACT (Reactant or Reagent). 16426-64-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrNO4, Related Products of 16426-64-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary