In 2019,Russian Journal of General Chemistry included an article by Yakantham, T.; Sreenivasulu, R.; Raju, R. R.. Formula: C7H5BrO2. The article was titled 《Design, Synthesis, and Anticancer Evaluation of 2-{3-{4-[(5-Aryl-1,2,4-oxadiazol-3-yl)methoxy]phenyl}isoxazol-5-yl}-N-(3,4,5-trimethylphenyl)thiazol-4-amine Derivatives》. The information in the text is summarized as follows:
A series of new 2-(3-(4-[(5-aryl-1,2,4-oxadiazol-3-yl)methoxy]phenyl)isoxazol-5-yl)-N-(3,4,5-tri-methylphenyl)thiazol-4-amine derivatives I (R = H, MeO, NO2; R1 = H, MeO, Br, Cl, Me, NO2; R2 = H, MeO, NO2) is synthesized, and the structures of products are confirmed by 1H and 13C NMR, and mass spectra. The new compounds I are tested for their anticancer activity against human cancer cell lines: MCF-7 (breast), A549 (lung), Du-145 (prostate), and MDA MB-231 (breast) by using MTT assay and etoposide as a standard reference All compounds I demonstrate good to moderate activity on all cell lines.4-Bromobenzoic acid(cas: 586-76-5Formula: C7H5BrO2) was used in this study.
4-Bromobenzoic acid(cas: 586-76-5) has been used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.Formula: C7H5BrO2 It was used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary