Yadav, Rahul; Darakshan; Bhaumick, Prabhas; Choudhury, Lokman H.; Parvin, Tasneem published the artcile< Synthesis of Pentacyclic Pyran Fused Pyrazolo Benzo[h]quinolines by Multicomponent Reaction and Their Photophysical Studies>, SDS of cas: 3893-18-3, the main research area is pentacyclic pyranpyrazolobenzoquinoline preparation photophys study; aldehyde hydroxy naphthoquinone aminopyrazole one pot three component reaction.
A one-pot method for the synthesis of pentacyclic pyran fused pyrazolo benzo[h]quinolines I (R1 = Ph, 4-chlorophenyl, anthracen-9-yl, etc.; R2 = Me, Ph, 4-methylphenyl, 4-chlorophenyl; R3 = Me, Ph, 4-methylphenyl) in acetic acid medium from the three-component reaction of 2-hydroxy-1,4-naphthoquinone, α, β-unsaturated aldehydes and 5-aminopyrazoles under the reflux conditions has been described. In this reaction, four new bonds (2 C-C, 1 C-N and 1 C-O) and two new rings (pyridine and pyran) were formed in one-pot. The novel products contain four bioactive moieties such as pyran, pyridine, pyrazole and α-naphthol. The salient features of this method are: one-pot process, short reaction time, easier purification, no need of column chromatog. and good yields of the products I. All the products I were characterized by IR, NMR and HRMS. Most of the synthesized compounds I were found highly fluorescent. Therefore, their photophys. properties were studied by UV-Visible and Fluorescence spectroscopy. Their quantum yields which were calculated and found in the range 0.243-0.424 in CHCl3 solution (c = 10-5 M) have been reported. Compound I (R1 = phenyl; R2 = phenyl; R3 = methyl) showed the highest quantum yield of 0.424.
ChemistrySelect published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, SDS of cas: 3893-18-3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary