Xu, Yuliang’s team published research in Organic Chemistry Frontiers in 2019 | 3959-07-7

Organic Chemistry Frontiers published new progress about Amines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Product Details of C7H8BrN.

Xu, Yuliang; Xu, Ze-Jun; Liu, Zhao-Peng; Lou, Hongxiang published the artcile< Visible-light-mediated de-aminative alkylation of N-arylamines with alkyl Katritzky salts>, Product Details of C7H8BrN, the main research area is alkyl tetrahydroisoquinoline preparation; tetrahydroisoquinoline Katritzky salt deaminative alkylation photochem; aryl alkyl aminoester preparation; Katritzky salt aryl aminoester deaminative alkylation photochem.

A visible-light-mediated de-aminative alkylation of N-arylamines was developed, providing direct access to α-amino C-H functionalization of N-arylamines from readily available Katritzky salts under mild conditions to get tetrahydroisoquinolines, e.g., I, and alkyl-N-aryl-aminoesters, e.g., II. In some cases, this operationally simple protocol could be performed in the absence of a photocatalyst. A wide range of substrates and functional groups were tolerated. The utility of this approach was highlighted by its application to the late-state modification of drug mols., natural products and peptides.

Organic Chemistry Frontiers published new progress about Amines Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Product Details of C7H8BrN.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary