Product Details of 21085-72-3In 2019 ,《Extended scaffold glucuronides: en route to the universal synthesis of O-aryl glucuronide prodrugs》 appeared in Organic & Biomolecular Chemistry. The author of the article were Walther, Raoul; Jarlstad Olesen, Morten T.; Zelikin, Alexander N.. The article conveys some information:
We demonstrate that an extended scaffold based on a self-immolative linker (SIL) enables the universal production of O-aryl glucuronide prodrugs: high yield glucuronidation is performed on a precursor substrate (SIL) and the subsequent drug conjugation proceeds via less challenging chem. reactions. The results came from multiple reactions, including the reaction of (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3Product Details of 21085-72-3)
(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3) may be used for the synthesis of HMR1098-S-Glucuronide Methyl Ester, a new K-ATP-blocking agent being developed as a drug for prevention of sudden cardiac death.Product Details of 21085-72-3
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary