Tang, Shibing; He, Jinmei; Sun, Yongquan; He, Liuer; She, Xuegong published the artcile< Efficient and Regioselective One-Pot Synthesis of 3-Substituted and 3,5-Disubstituted Isoxazoles>, Electric Literature of 3893-18-3, the main research area is isoxazole regioselective preparation; hydroxyl toluenesulfonamide unsaturated aldehyde ketone conjugate addition cyclization.
A series of 3-substituted and 3,5-disubstituted isoxazoles have been efficiently synthesized in moderate to excellent yields by the reaction of N-hydroxyl-4-toluenesulfonamide with α,β-unsaturated aldehydes/ketones. This novel strategy is associated with readily available starting materials, mild conditions, high regioselectivity, and wide scope.
Organic Letters published new progress about Conjugate addition reaction. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Electric Literature of 3893-18-3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary