Smith, Philip J.; Jiang, Yubo; Tong, Zixuan; Pickford, Helena D.; Christensen, Kirsten E.; Nugent, Jeremy; Anderson, Edward A. published the artcile< Synthesis of Polysubstituted Fused Pyrroles by Gold-Catalyzed Cycloisomerization/1,2-Sulfonyl Migration of Yndiamides>, Safety of 4-Bromobenzylamine, the main research area is alkynylyndiamide gold catalyst regioselective cycloisomerization sulfonyl migration; tetrahydropyrrolopyrrole preparation.
Yndiamides (bis-N-substituted alkynes) are valuable precursors to azacycles. A cycloisomerization/1,2-sulfonyl migration of alkynyl-yndiamides to form tetrahydropyrrolopyrroles, unprecedented heterocyclic scaffolds that are relevant to medicinal chem were reported. This functional group tolerant transformation was achieved using Au(I) catalysis that proceeded at ambient temperature and a thermally promoted process. The utility of the products was demonstrated by a range of reactions to functionalize the fused pyrrole core.
Organic Letters published new progress about Alkynes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Safety of 4-Bromobenzylamine.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary