Saikia, Rakhee; Park, Kwihwan; Masuda, Hayato; Itoh, Miki; Yamada, Tsuyoshi; Sajiki, Hironao; Mahanta, Sanjeev P.; Thakur, Ashim J.; Bora, Utpal published an article in 2021. The article was titled 《Revisiting the synthesis of aryl nitriles: a pivotal role of CAN》, and you may find the article in Organic & Biomolecular Chemistry.Synthetic Route of C7H5BrO2 The information in the text is summarized as follows:
Facilitated by the dual role of ceric ammonium nitrate (CAN), herein a cost-effective approach for the cyanation of aryl iodides/bromides with CAN-DMF as an addition to the existing pool of combined cyanation sources was reported. In addition to being an oxidant, CAN acted as a source of nitrogen in our protocol. The reaction was catalyzed by a readily available Cu(II) salt and the ability of CAN to generate ammonia in the reaction medium was utilized to eliminate the addnl. requirement of a nitrogen source, ligand, additive or toxic reagents. The mechanistic study suggested an evolution of CN- leading to the synthesis of a variety of aryl nitriles ArCN [Ar = Ph, 4-OHC6H4, 4-H2NC6H4, etc.] in moderate to good yields. The proposed mechanism was supported by a series of control reactions and labeling experiments After reading the article, we found that the author used 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Synthetic Route of C7H5BrO2)
Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Synthetic Route of C7H5BrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary