COA of Formula: C4H6BrFO2On October 21, 2020 ,《Cobalt-Catalyzed α-Arylation of Substituted α-Bromo α-Fluoro β-Lactams with Diaryl Zinc Reagents: Generalization to Functionalized Bromo Derivatives》 was published in Chemistry – A European Journal. The article was written by Lorion, Melanie M.; Koch, Vanessa; Nieger, Martin; Chen, Hi-Yung; Lei, Aiwen; Braese, Stefan; Cossy, Janine. The article contains the following contents:
A cobalt-catalyzed cross-coupling of α-bromo α-fluoro β-lactams with diarylzinc or diallylzinc reagents is herein disclosed. The protocol proved to be general, chemoselective and operationally simple allowing the C4 functionalization of β-lactams. The substrate scope was expanded to α-bromo lactams and amides, α-bromo lactones and esters as well as N- and O-containing heterocycles. In the experiment, the researchers used Ethylbromofluoroacetate(cas: 401-55-8COA of Formula: C4H6BrFO2)
Ethylbromofluoroacetate(cas: 401-55-8) is a member of organofluorine compounds. Organofluorine compounds, which have carbon-fluorine bonds, show unique features such as high thermal and chemical stability, high surface activity, no light-absorbing ability, high pharmacological effect, and so on. Owing to their specific characters, they are indispensable chemicals for industry and our daily lives.COA of Formula: C4H6BrFO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary