《Catalytic Reductions Without External Hydrogen Gas: Broad Scope Hydrogenations with Tetrahydroxydiboron and a Tertiary Amine》 was published in Advanced Synthesis & Catalysis in 2020. These research results belong to Korvinson, Kirill A.; Akula, Hari K.; Malinchak, Casina T.; Sebastian, Dellamol; Wei, Wei; Khandaker, Tashrique A.; Andrzejewska, Magdalena R.; Zajc, Barbara; Lakshman, Mahesh K.. Synthetic Route of C7H5BrO2 The article mentions the following:
Aryl bromides, iodides, chlorides, and triflates, benzylic halides and ethers, benzyl carbamates, alkenes, alkynes, azides, and aldehydes underwent reductive cleavage, hydrogenation, and reduction reactions using B2(OH)4 as reductant in the presence of Pd/C and 4-methylmorpholine. Aryl dihalides containing two different halogen atoms underwent selective reduction, with reduction of I favored over reduction of Br and Cl, and Br reduction favored over the reduction of Cl. Cyano groups were unaffected, but nitro group and ketones underwent reduction to a low extent. B2(OD)4 and N,N-bis(methyl-d3)pyridin-4-amine (DMAP-d6) were used as reagents for the reductive deuteration of aryl halides. Hydrogen gas has been observed to form with this reagent combination.4-Bromobenzoic acid(cas: 586-76-5Synthetic Route of C7H5BrO2) was used in this study.
4-Bromobenzoic acid(cas: 586-76-5) has been used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.Synthetic Route of C7H5BrO2 It was used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary