Reference of o-BromobenzaldehydeIn 2019 ,《A Microwave Accelerated Sustainable Approach for the Synthesis of 2-amino-4H-chromenes Catalyzed by WEPPA: A Green Strategy》 appeared in Current Microwave Chemistry. The author of the article were Hiremath, Prashant B.; Kamanna, Kantharaju. The article conveys some information:
We established an efficient, simple, agro-waste based catalytic approach for the synthesis of 2-amino-4H-chromene derivatives I [R1 = H, 2-Cl, 4-MeO, etc.], II [ R2 = H, 4-Me, 2-Cl, 4-Cl, 4-MeO] and III [R3 = H, 4-OH, 3-NO2, etc.] from the condensation of arylaldehyde, malononitrile and resorcinol/α-naphthol/β-naphthol employing WEPPA as an efficient catalyst under microwave synthesis. The method was found to be a greener, economic and eco-friendly approach for the synthesis of chromene scaffolds. The advantages of the present approach were solvent-free, no external metal, chem. base free, short reaction time and isolated product in good to excellent yields. The catalyst was agro-waste derived, which has abundant natural sources available, thus making the present approach a greener one. After reading the article, we found that the author used o-Bromobenzaldehyde(cas: 6630-33-7Reference of o-Bromobenzaldehyde)
o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.Reference of o-BromobenzaldehydeIt is also used in L-threonine aldolase-catalyzed enantio and diastereoselective aldol reactions. Further, it reacts with trichloromethane to prepare 1-(2-bromo-phenyl)-2,2,2-trichloro-ethanol.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary