Computed Properties of C6H5BrO2On May 1, 2021 ,《A Practical and Efficient Synthesis of Uniform Conjugated Rod-Like Oligomers》 appeared in Macromolecular Rapid Communications. The author of the article were Hahn, Daniel; Schneider, Rebekka V.; Foitzik, Elena; Meier, Michael A. R.. The article conveys some information:
Herein, a more practical and efficient synthesis protocol for the preparation of uniform rod-like oligo(1,4-phenylene ethynylene)s (OPE)s is presented. Applying an iterative reaction cycle consisting of a decarboxylative coupling reaction and a saponification of an alkynyl carboxylic ester, a uniform pentamer is obtained in ten steps with 14% overall yield. The copper-free conditions prevent homocoupling until the trimer stage, resulting in a significantly easier work-up of the products. Homocoupling is observed from the tetramer stage on, but a simple variation of the work-up procedure also yields the uniform tetramer and pentamer. A thorough comparison with the commonly used and described Sonogashira approach reveals that with the new presented strategy, OPEs can be built in similar overall yield, but easier purification and in a quarter of the time. All oligomers are fully characterized by proton and carbon NMR spectroscopy (NMR), mass spectrometry (MS), size-exclusion chromatog. (SEC), and IR spectroscopy (IR). After reading the article, we found that the author used 2-Bromobenzene-1,4-diol(cas: 583-69-7Computed Properties of C6H5BrO2)
2-Bromobenzene-1,4-diol(cas: 583-69-7) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Due to the reactivity of bromide, they are used as potential precursors or important intermediates in organic synthesis. Computed Properties of C6H5BrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary