Ban, Jaeyoung; Lim, Minkyung; Shabbir, Saira; Baek, Junghyun; Rhee, Hakjune published the artcile< Site-Specific Synthesis of Carbazole Derivatives through Aryl Homocoupling and Amination>, Synthetic Route of 51605-97-1, the main research area is carbazole preparation; aniline acetylation Ullmann homocoupling intramol amination.
Author synthesized various carbazoles I (R = H, 2,7-Me, 3,6-F, etc.) from anilines through a three-step process with good overall yields (up to 48%). This process comprises N-acetylation, copper(0)-mediated Ullmann homocoupling, and acid-mediated intramol. amination. It permits various functional groups on the substrate. Scale-up of the developed three-step synthetic route to carbazoles was also demonstrated.
Synthesis published new progress about Acetylation. 51605-97-1 belongs to class bromides-buliding-blocks, and the molecular formula is C9H12BrN, Synthetic Route of 51605-97-1.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary