Application In Synthesis of 3,6-Dibromo-9H-carbazoleIn 2019 ,《Analysis of polyhalogenated carbazoles in sediment using liquid chromatography-tandem mass spectrometry》 was published in Ecotoxicology and Environmental Safety. The article was written by Zhou, Wenxiu; Huang, Xinwen; Lin, Kunde. The article contains the following contents:
The purpose of this study was to develop a novel and sensitive method for the anal. of carbazole and polyhalogenated carbazoles (PHCs) in sediment using ultra performance liquid chromatog.-tandem mass spectrometry (UPLC-MS/MS). Briefly, 5.0 g of freeze-dried sediment samples were extracted with dichloromethane using pressurized liquid extraction (PLE). The extract was purified with Florisil solid phase extraction cartridge, filtered through 0.22μm polytetrafluoroethylene filter using a glass syringe, followed by LC-MS/MS anal. Besides parameters for LC-MS/MS anal., sample preparation procedures (including solvents for PLE, sorbents for cleanup, and filters for sample filtration) were optimized. The limits of detection and limits of quantification of target compounds were in the ranges of 3.0 × 10-3 to 0.22 ng g-1 dry weight (d.w.) and 1.0 × 10-2 to 0.75 ng g-1 d.w., resp. The recoveries of target compounds in the spiked sediments at 2.0 ng g-1 d.w. and 10 ng g-1 d.w. were 64.8-91.8% and 70.9-124.7%, resp., with relative standard deviations being less than 13.2%. Except that 36-BCZ had pos. matrix effects of 63.3%, the sediment matrixes generally displayed low or medium neg. matrix effects on the other target compounds during LC-MS/MS anal. The developed method was applied in the anal. of carbazoles and PHCs in sediment samples from Jiulong River, Fujian, China and all the target compounds were detected in the samples. In the experiment, the researchers used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Application In Synthesis of 3,6-Dibromo-9H-carbazole)
3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Application In Synthesis of 3,6-Dibromo-9H-carbazole
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary