In 2017,Zhao, Huai-Bo; Hou, Zhong-Wei; Liu, Zhan-Jiang; Zhou, Ze-Feng; Song, Jinshuai; Xu, Hai-Chao published 《Amidinyl Radical Formation through Anodic N-H Bond Cleavage and Its Application in Aromatic C-H Bond Functionalization》.Angewandte Chemie, International Edition published the findings.Computed Properties of C6H5Br2N The information in the text is summarized as follows:
We report herein an atom-economical and sustainable approach to access amidinyl radical intermediates through the anodic cleavage of N-H bonds. The resulting nitrogen-centered radicals undergo cyclizations with (hetero)arenes, followed by rearomatization, to afford functionalized tetracyclic benzimidazoles, e.g., I (X-rays crystal structure shown), in a highly straightforward and efficient manner. This metal- and reagent-free C-H/N-H cross-coupling reaction exhibits a broad substrate scope and proceeds with high chemoselectivity. The experimental part of the paper was very detailed, including the reaction process of 3,5-Dibromoaniline(cas: 626-40-4Computed Properties of C6H5Br2N)
3,5-Dibromoaniline(cas: 626-40-4) belongs to anime. Large quantities of aliphatic amines are made synthetically. The most widely used industrial method is the reaction of alcohols with ammonia at a high temperature, catalyzed by metals or metal oxide catalysts (e.g., nickel or copper). Mixtures of primary, secondary, and tertiary amines are thereby produced.Computed Properties of C6H5Br2N
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary