Yakovenko, Georgiy G.; Yagodkina, Marta S.; Bol’but, Andriy V.; Shishkina, Svitlana V.; Vovk, Mykhailo V. published the artcile< Synthesis of new triazolo[1,5-b][2,4]benzodiazepines via tandem cyclization of o-(azidomethyl)benzoates with cyanoacetamides>, Electric Literature of 337536-14-8, the main research area is crystal mol structure bromo methylpiperazine benzo triazole diazepinone; tandem cyclization azidomethy benzoate cyanoacetamide; triazolo benzodiazepine preparation tandem cyclization.
Based on the tandem anionic cyclization of o-(azidomethyl)benzoates with 2-cyanoacetamides, an efficient synthetic route to the hitherto unknown heterocyclic system, triazolo[1,5-b][2,4]benzodiazepine, has been developed. The optimum reaction conditions have been found which provide 59-74% yields of target compounds Their structural determination has been performed by the IR, LCMS, and NMR spectral methods as well as by X-ray diffraction anal.
Monatshefte fuer Chemie published new progress about Active methylene compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 337536-14-8 belongs to class bromides-buliding-blocks, and the molecular formula is C9H8Br2O2, Electric Literature of 337536-14-8.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary