Vankadari, Srinivas Rao’s team published research in Medicinal Chemistry Research in 2013 | CAS: 76006-33-2

3-Bromo-2-methylbenzoic acid(cas: 76006-33-2) belongs to organobromine compounds.Organobromine chemicals are produced naturally by an array of biological and other chemical processes in our environment. COA of Formula: C8H7BrO2Some of these compounds are identical to man-made organobromine compounds, such as methyl bromide, bromoform, and bromophenols, but many others are entirely new moleclar entities, often possessing extraordinary and important biological properties.

In 2013,Vankadari, Srinivas Rao; Mandala, Devender; Pochampalli, Jalapathi; Tigulla, Parthasarathy; Valeru, Anil; Thampu, Rajakomuraiah published 《Synthesis, evaluation of antimicrobial activity, and molecular modeling of novel 2-((4-(2H-benzo[d] [1,2,3] triazol-2-yl)piperidin-1-yl)methyl)-5-substituted phenyl-1,3,4-oxadiazoles》.Medicinal Chemistry Research published the findings.COA of Formula: C8H7BrO2 The information in the text is summarized as follows:

A new series of 2-((4-(2H-benzo[d][1,2,3]triazol-2-yl)piperidin-1-yl)methyl)-5-substituted-phenyl-1,3,4-oxadiazoles I [Ar = Ph, 2-Br-Ph, 3-MeOPh, 3-NO2Ph, etc.] were synthesized by cyclization of 4-((benzotriazol-2-yl)-piperidin-1-yl)-acetic acid hydrazide with various substituted aromatic carboxylic acids in the presence of POCl3. The structures were characterized by spectral data. The representative examples were screened in vitro antibacterial activity and antifungal activity. The compounds showed significant antibacterial activity and showed moderate antifungal activity as that of standards, resp. The data were further compared with structure-based investigations using docking studies with the crystal structure of oxidoreductase (1XDQ) protein organism: Escherichia coli for antibacterial activity and oxidoreductase (3QLS) protein, organism: Candida albicans for antifungal activity. The score values estimated by genetic algorithm were found to have a good correlation with the exptl. inhibitory potencies. The experimental part of the paper was very detailed, including the reaction process of 3-Bromo-2-methylbenzoic acid(cas: 76006-33-2COA of Formula: C8H7BrO2)

3-Bromo-2-methylbenzoic acid(cas: 76006-33-2) belongs to organobromine compounds.Organobromine chemicals are produced naturally by an array of biological and other chemical processes in our environment. COA of Formula: C8H7BrO2Some of these compounds are identical to man-made organobromine compounds, such as methyl bromide, bromoform, and bromophenols, but many others are entirely new moleclar entities, often possessing extraordinary and important biological properties.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary