Shyam, Radhe; Forestier, Christiane; Charbonnel, Nicolas; Roy, Olivier; Taillefumier, Claude; Faure, Sophie published an article in 2021. The article was titled 《Solution-phase synthesis of backbone-constrained cationic peptoid hexamers with antibacterial and anti-biofilm activities》, and you may find the article in European Journal of Organic Chemistry.SDS of cas: 5437-45-6 The information in the text is summarized as follows:
Submonomer synthesis in solution and block-coupling protocols were combined to prepare amphiphilic peptoid hexamers. The amphipathic character arises from the use of hydrophobic aliphatic tert-Bu side-chains imposing the cis-amide backbone conformation and various cationic side-chains periodically introduced each three residues. Evaluation of the effect on Gram-pos. and Gram-neg. bacterial strains as well as the capacity to impair biofilm formation and the toxicity of one selected compound allowed to highlight the potential of a short constrained peptoid carrying triazolium-type cationic pendant groups. In addition to this study using Benzyl 2-bromoacetate, there are many other studies that have used Benzyl 2-bromoacetate(cas: 5437-45-6SDS of cas: 5437-45-6) was used in this study.
Benzyl 2-bromoacetate(cas: 5437-45-6) has been used in the alkylation of (-)-2,3-O-isopropylidene-D-threitol that afforded lipopeptide, 2-[(4R,5R)-5-({[(9H-fluoren-9-yl)methoxy]carbonylaminomethyl}-2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]acetic acid.SDS of cas: 5437-45-6
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary