《A Concise Total Synthesis of (+)-Waihoensene Guided by Quaternary Center Analysis》 was written by Peng, Cheng; Arya, Piyush; Zhou, Zhiyao; Snyder, Scott A.. Application of 1779-49-3This research focused onwaihoensene total synthesis Conia ene cyclization Pauson Khand; Conia-ene; Pauson-Khand; total synthesis; triquinanes; waihoensene. The article conveys some information:
The four contiguous all-carbon quaternary centers of waihoensene (I), coupled with the absence of any traditional reactive functional groups other than a single alkene, render it a particularly challenging synthetic target among angular triquinane natural products. Here, we show that its polycyclic frame can be assembled concisely by using a strategically chosen quaternary center to guide the formation of the other three through judiciously selected C-C bond formation reactions. Those events, which included a unique Conia-ene cyclization and a challenging Pauson-Khand reaction, afforded a 17-step synthesis of the mol. in enantioenriched form. In the experimental materials used by the author, we found Methyltriphenylphosphonium bromide(cas: 1779-49-3Application of 1779-49-3)
Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.Application of 1779-49-3
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary