McCarney, Eoin P.; McCarthy, William J.; Lovitt, June I.; Gunnlaugsson, Thorfinnur published their research in Organic & Biomolecular Chemistry in 2021. The article was titled 《Macrocyclic vs. [2]catenane btp structures: influence of (aryl) substitution on the self templation of btp ligands in macrocyclic synthesis》.Recommanded Product: 1129-28-8 The article contains the following contents:
The synthesis of four 2,6-bis(1,2,3-triazol-4-yl)pyridine (btp) olefin based ligands I (n = 1, 9) and II (n = 3, 9) and their attempted use to form mech. interlocked mols. using ring closing metatheses (RCM) reactions are described. The btp ligands were modified in two ways, in I the aryl substitution pattern was changed from 4th position to 3rd position and in the case of II, the arms were replaced with aliphatic chains. This study demonstrates that for all four ligands I and II, the RCM reactions only result in the formation of macrocyclic structures, which in three of the cases, were structurally characterized in both solution (using NMR and HRMS) and in the solid-state using X-ray crystallog. NMR studies were also carried out to investigate if these ligands could preorganize in solution via hydrogen bonding interactions. This study provides a handle of how such precursor substitution can be used to direct the formation of macrocycles or mech. interlocked structures. The experimental process involved the reaction of Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8Recommanded Product: 1129-28-8)
Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Recommanded Product: 1129-28-8 Due to the reactivity of bromide, they are used as potential precursors or important intermediates in organic synthesis.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary