《One-pot synthesis of porphyrin-based [5]rotaxanes》 was published in Organic & Biomolecular Chemistry in 2020. These research results belong to Martinez-Bulit, Pablo; Wilson, Benjamin H.; Loeb, Stephen J.. Synthetic Route of C6H5Br2N The article mentions the following:
A one-pot reaction is used to make a series of [5]rotaxanes. The protocol involves simultaneous threading-followed-by-stoppering to trap a macrocycle (dibenzo[24]crown-8, DB24C8) on an axle to form a mech. interlocked mol. (MIM) – in this case a rotaxane – and the condensation of an aldehyde with a pyrrole to form a porphyrin precursor. For each [5]rotaxane, a different combination of recognition site and stoppering group was used; the protonation state of the [5]rotaxane can be used to generate different co-conformational states for each [5]rotaxane making these systems potential multi-state switches for further study in solution or the solid-state. In the experimental materials used by the author, we found 3,5-Dibromoaniline(cas: 626-40-4Synthetic Route of C6H5Br2N)
3,5-Dibromoaniline(cas: 626-40-4) belongs to anime. The reaction of alkyl halides, R―X, where X is a halogen, or analogous reagents with ammonia (or amines) is useful with certain compounds. Not all alkyl halides are effective reagents; the reaction is sluggish with secondary alkyl groups and fails with tertiary ones. Its usefulness is largely confined to primary alkyl halides (those having two hydrogen atoms on the reacting site).Synthetic Route of C6H5Br2N
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary