Kim, Ju-Hye; Park, Eun-Jin; Lee, Hwa-Jung; Ho, Xuan-Huong; Yoon, Hyo-Sang; Kim, Pilsoo; Yun, Hoseop; Jang, Hye-Young published the artcile< Tandem Iminium/Copper Catalysis: Highly Enantioselective Synthesis of α,β-Disubstituted Aldehydes>, COA of Formula: C9H7BrO, the main research area is iminium copper catalyst enantioselective aldehyde Michael addition.
With the goal of synthesizing biol. and synthetically valuable products under environmentally benign and economic conditions, an asym. organocatalytic reaction was combined with a copper catalytic reaction. This iminium/copper catalysis allowed highly optically active α,β-disubstituted aldehydes to be synthesized with good yields in one-pot fashion. The β-substitution took place through iminium-catalyzed Michael addition of nitromethane or di-Et malonate to the α,β-unsaturated aldehydes, followed by copper-assisted addition of TEMPO (2,2,6,6-tetramethylpiperidin-1-yloxyl) at the aldehyde α-position. An iminium/copper-catalyzed tandem addition product was converted into a 3,4,5-trisubstituted piperidine for x-ray crystallog. anal.
European Journal of Organic Chemistry published new progress about Crystal structure. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, COA of Formula: C9H7BrO.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary