Grassl, Simon; Hamze, Clemence; Koller, Thaddaeus J.; Knochel, Paul published the artcile< Copper-Catalyzed Electrophilic Thiolation of Organozinc Halides by Using N-Thiophthalimides Leading to Polyfunctional Thioethers>, COA of Formula: C9H11Br, the main research area is organozinc halide thiophthalimide copper catalyst electrophilic thiolation; thioether thiocyanate selenide preparation; copper catalysis; electrophilic thiolation; organozinc halides; thioethers; trifluoromethylthioation.
(Hetero)aryl, benzylic, and alkyl zinc halides were thiolated with N-thiophthalimides at 25 °C within 1 h in the presence of 5-10 % Cu(OAc)2·H2O to furnish the corresponding polyfunctionalized thioethers in good yields. This electrophilic thiolation was extended to the introduction of trifluoromethylthio (SCF3), thiocyanate (SCN), and selenophenyl (SePh) groups. The utility of this method was shown in a seven-step synthesis of a potent cathepsin D inhibitor in 34% overall yield.
Chemistry – A European Journal published new progress about Aryl halides Role: RCT (Reactant), RACT (Reactant or Reagent). 576-83-0 belongs to class bromides-buliding-blocks, and the molecular formula is C9H11Br, COA of Formula: C9H11Br.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary