Goldberg, Frederick W.; Kettle, Jason G.; Xiong, Jian; Lin, Daoguang published the artcile< General synthetic strategies towards N-alkyl sulfoximine building blocks for medicinal chemistry and the use of dimethylsulfoximine as a versatile precursor>, COA of Formula: C7H4BrNO4, the main research area is alkyl sulfoximine preparation; sulfide amination oxidation alkylation.
The sulfoximine group has great potential as a substituent in drug discovery, as evidenced by two new clin. candidates, and can be viewed as an isosteric alternative to the commonly used sulfone. Our aim was to improve the accessibility of this group by synthesizing a diverse range of S-alkyl and N-alkyl sulfoximine building blocks with procedures that are applicable on a practical scale (>10 g). In particular, synthesis of the less well exploited N-alkyl sulfoximines and the use of dimethylsulfoximine as a versatile, com. available precursor is discussed.
Tetrahedron published new progress about Alkylation. 16426-64-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrNO4, COA of Formula: C7H4BrNO4.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary