Gao, Jihui; Jiao, Mingdong; Ni, Jie; Yu, Rongrong; Cheng, Gui-Juan; Fang, Xianjie published an article in 2021. The article was titled 《Nickel-Catalyzed Migratory Hydrocyanation of Internal Alkenes: Unexpected Diastereomeric-Ligand-Controlled Regiodivergence》, and you may find the article in Angewandte Chemie, International Edition.Synthetic Route of C20H20BrP The information in the text is summarized as follows:
A regiodivergent nickel-catalyzed hydrocyanation of a broad range of internal alkenes involving a chain-walking process is reported. When appropriate diastereomeric biaryl diphosphite ligands are applied, the same starting materials can be converted to either linear or branched nitriles with good yields and high regioselectivities. DFT calculations suggested that the catalyst architecture determines the regioselectivity by modulating electronic and steric interactions. In addition, moderate enantioselectivities were observed when branched nitriles were produced. After reading the article, we found that the author used Ethyltriphenylphosphonium bromide(cas: 1530-32-1Synthetic Route of C20H20BrP)
Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. CatOnium ETPB is also used as catalysts in the synthesis of certain organic compounds.Synthetic Route of C20H20BrP
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary