Chen, Lian-Mei; Zhao, Juan; Xia, An-Jie; Guo, Xiao-Qiang; Gan, Ya; Zhou, Chuang; Yang, Zai-Jun; Yang, Jun; Kang, Tai-Ran published the artcile< A base-promoted cascade reaction of α,β-unsaturated N-tosylhydrazones with o-hydroxybenzyl alcohols: highly regioselective synthesis of N-sec-alkylpyrazoles>, HPLC of Formula: 3893-18-3, the main research area is hydroxymethyl arylalc arylethenyl tosylhydrazone base tandem heterocyclization aza Michael; arylpyrazolylmethyl aryl alc preparation regioselective.
An efficient method for the synthesis of N-sec-alkylpyrazoles through a base-promoted cascade cyclization/Michael addition reaction of α,β-unsaturated N-tosylhydrazones with ortho-hydroxybenzyl alcs. was developed. The desired products containing di- or triaryl groups at the same carbon atom were afforded in good to excellent yields with excellent regioselectivities (>20 : 1). Moreover, a three-component reaction of ortho-hydroxybenzyl alcs., α,β-unsaturated N-tosylhydrazones and saturated N-tosylhydrazones also took place to afforded pyrazoles in good yields. This reaction offered a new route to triarylmethanes with a simple operation and was applicable for large-scale synthesis.
Organic & Biomolecular Chemistry published new progress about Alkylarenes Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, HPLC of Formula: 3893-18-3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary