Blass, Benjamin E.; Chen, Peng-Jen; Taylor, Michelle; Griffin, Suzy A.; Gordon, John C.; Luedtke, Robert R. published the artcile< Synthesis and evaluation of cyclic diamino benzamide based D3 receptor ligands>, Product Details of C7H4BrF3, the main research area is cyclic diamino benzamide preparation D3 receptor pharmacokinetics.
Dopamine is a key neurotransmitter whose impact on pharmacol. processes is mediated by a family of dopamine receptors designated D1, D2, D3, D4 and D5. Various diseases and conditions such as schizophrenia, drug abuse, depression, restless leg syndrome, Parkinson′s disease (PD), and inflammatory diseases have been linked to aberrant D3 activity. Herein, we report a series of novel D3 ligands with improved solubility over our previous lead compound, MC25-41 (2).
Medicinal Chemistry Research published new progress about Brain. 401-78-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3, Product Details of C7H4BrF3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary