The author of 《CuH-Catalyzed Asymmetric Hydroamidation of Vinylarenes》 were Zhou, Yujing; Engl, Oliver D.; Bandar, Jeffrey S.; Chant, Emma D.; Buchwald, Stephen L.. And the article was published in Angewandte Chemie, International Edition in 2018. COA of Formula: C8H4BrF3O2 The author mentioned the following in the article:
A CuH-catalyzed enantioselective hydroamidation reaction of vinylarenes was developed using readily accessible 1,4,2-dioxazol-5-ones as electrophilic amidating reagents. This method provides a straightforward and efficient approach to synthesize chiral amides in good yields with high levels of enantiopurity under mild conditions. Moreover, this transformation tolerates substrates bearing a broad range of functional groups. The experimental process involved the reaction of 3-Bromo-4-(trifluoromethoxy)benzaldehyde(cas: 85366-66-1COA of Formula: C8H4BrF3O2)
3-Bromo-4-(trifluoromethoxy)benzaldehyde(cas: 85366-66-1) belongs to organobromine compounds.The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. COA of Formula: C8H4BrF3O2 The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary