Safety of Methyl 3-(bromomethyl)benzoateIn 2020 ,《Silaboration of [1.1.1]Propellane: A Storable Feedstock for Bicyclo[1.1.1]pentane Derivatives》 was published in Angewandte Chemie, International Edition. The article was written by Kondo, Masaki; Kanazawa, Junichiro; Ichikawa, Tomohiro; Shimokawa, Takumi; Nagashima, Yuki; Miyamoto, Kazunori; Uchiyama, Masanobu. The article contains the following contents:
The silaboration of [1.1.1]propellane enables direct introduction of B and Si functional groups onto the bicyclo[1.1.1]pentane (BCP) scaffold in high yield under mild, additive-free conditions. The silaborated BCP can be obtained on a gram-scale in a single step without the need for column-chromatog. purification, and is storable and easy to handle, providing a versatile synthetic intermediate for BCP derivatives We also describe various conversions of the C-B/C-Si bonds on the BCP scaffold, including development of a modified Suzuki-Miyaura cross-coupling reaction at the highly sterically hindered bridgehead sp3 carbon center of the BCP skeleton using a combination of highly activated BCP boronic esters, copper(I) oxide, and a PdCl2(dppf) catalyst system. In the experiment, the researchers used many compounds, for example, Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8Safety of Methyl 3-(bromomethyl)benzoate)
Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Alkyl bromides are mainly used as alkylating agents and also find application as a solvent to extract oil from seeds and wool. Safety of Methyl 3-(bromomethyl)benzoate
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary