In 2019,European Journal of Organic Chemistry included an article by Kianmehr, Ebrahim; Nasab, Sepideh Bahrami. Category: bromides-buliding-blocks. The article was titled 《Ruthenium-Catalyzed Regioselective Direct Ortho-Acyloxylation of Azoarenes with Carboxylic Acids via C-H Bond Activation》. The information in the text is summarized as follows:
A highly regio and chemo-selective procedure for the synthesis of ortho-acyloxy-azoarene derivatives I [R = H, 4-Me, 4-Cl, etc.; R1 = H, 3-Et, 4-OH, etc.; R2 = i-Pr, Ph, Bn, etc.] was described via Ru-catalyzed C-H acyloxylation of azoarenes with inexpensive alkyl and aryl carboxylic acids as an acyloxylation agent. The reaction demonstrated a broad substrate scope and good functional group tolerance.4-Bromobenzoic acid(cas: 586-76-5Category: bromides-buliding-blocks) was used in this study.
4-Bromobenzoic acid(cas: 586-76-5) has been used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.Category: bromides-buliding-blocks It was used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary