Safety of Ethyltriphenylphosphonium bromideIn 2021 ,《Ruthenium Removal Using Silica-Supported Aromatic Isocyanides》 was published in Journal of Organometallic Chemistry. The article was written by Gregg, Zackary R.; Glickert, Elise; Xu, Ruoshui; Diver, Steven T.. The article contains the following contents:
New silica gel scavengers containing aromatic isocyanides have been synthesized and evaluated for Ru removal. A thiol-ene click reaction was used to attach the isocyanide precursor to a thiol-containing siloxane. Conventional methods for grafting to silica gel at elevated temperature resulted in significant hydrolysis of the isocyanide. A novel cleavage reaction was developed to quantitate the amount of surface-loaded isocyanide. Binding by the new materials was comparatively evaluated for a variety or Ru carbene catalysts. The optimal conditions were extended to two ring-closing metatheses (RCM). The residual Ru was determined by inductively coupled plasma mass spectrometry (ICP-MS). For facile RCM reactions, the UV data agreed with the ICP-MS results. However, more difficult RCM did not correlate well with the UV data. This was interpreted in terms of varying extent of catalyst decomposition In all cases, isocyanide scavenger reagents were found to be superior to commonly used silica gel-based metal scavengers. The experimental process involved the reaction of Ethyltriphenylphosphonium bromide(cas: 1530-32-1Safety of Ethyltriphenylphosphonium bromide)
Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. CatOnium ETPB is also used as catalysts in the synthesis of certain organic compounds.Safety of Ethyltriphenylphosphonium bromide
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary