Strekalova, Sofia; Kononov, Alexander; Budnikova, Yulia published the artcile< Amino acids in electrochemical metal-free benzylic C-H amidation>, Recommanded Product: 2,4,6-Trimethylbromobenzene, the main research area is amide preparation; amino acid arene electrochem CH amidation.
This report described the mild electrochem. metal-, oxidant-, additive-free site-selective direct C-H amidation of benzyl C(sp3)-H bonds in an undivided cell using α-amino acids as a source of an amide bond moiety. Practically significant amides RCH2NHC(O)R1 [R = Ph, 3-MeC6H4, 4=BrC6H4; R1 = Me, i-Pr, Ph] were obtained under electrochem. mild one-pot conditions (without strong external oxidants, at room temperature), with total yields up to 73%. This electrochem. approach featured a functional selectivity and a broad scope of substrates with benzyl bond and different amino acids.
Tetrahedron Letters published new progress about Amidation. 576-83-0 belongs to class bromides-buliding-blocks, and the molecular formula is C9H11Br, Recommanded Product: 2,4,6-Trimethylbromobenzene.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary