Li, Peihe; Wang, Yingying; Wang, Xia; Wang, Yin; Liu, Ying; Huang, Keke; Hu, Jing; Duan, Limei; Hu, Changwen; Liu, Jinghai published the artcile< Selective Oxidation of Benzylic C-H Bonds Catalyzed by Cu(II)/{PMo12}>, Name: 1-Bromo-3-ethylbenzene, the main research area is selective oxidation benzylic carbon hydrogen bond copper polyoxometalate catalyst; ketone preparation selective oxidation benzylic carbon hydrogen mechanism.
Precise catalytic regulation of carbon radical generation by a highly active oxygen radical to abstract the H atom in a C-H bond is an effective method for the selective activation of C-H synthetic chem. Herein, we report a facile catalyst system with com. available copper(II)/{PMo12} to form a tert-butanol radical intermediate for the selective oxidation of benzylic C-H bonds. The reaction shows a broad range of substrates (benzyl methylene, benzyl alcs.) with good functional group tolerance and chem. selectivity. The corresponding carbonyl compounds were synthesized with good yields under mild conditions. DFT calculations and exptl. anal. further demonstrated a reasonable carbon radical mechanism for this type of organic transformation reaction.
Journal of Organic Chemistry published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 2725-82-8 belongs to class bromides-buliding-blocks, and the molecular formula is C8H9Br, Name: 1-Bromo-3-ethylbenzene.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary