Ghorbani-Choghamarani, Arash; Taherinia, Zahra published the artcile< New revolution in biaryl synthesis: transition metal-free C-C bond formation promoted by the mixture of 2-mercaptoethanol/KOH/DMSO>, Computed Properties of 401-78-5, the main research area is biaryl preparation; phenylboronic acid aryl halide transition metal free Suzuki type.
Biaryls RR1 [R = C6H5; R1 = C6H5, 3-MeOC6H4, 4-O2NC6H4, etc.] were synthesized via transition metal-free C-C cross coupling reaction of aryl halides with phenylboronic acid that was believed to be a new revolution in Suzuki type reactions. Carbon-carbon bond formation could be promoted by a mixture of 2-mercaptoethanol/KOH/DMSO without the aid of any transition metals. It has been suggested that this reaction proceeded through radical species, hence the electron transfer route was suggested for operation during oxidation of 2-mercaptoethanol in DMSO.
ChemistrySelect published new progress about Aryl halides Role: RCT (Reactant), RACT (Reactant or Reagent). 401-78-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3, Computed Properties of 401-78-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary