Zuo, Zhijun; Wang, Jing; Liu, Jingjing; Wang, Yaoyu; Luan, Xinjun published the artcile< Palladium-Catalyzed [2+2+1] Spiroannulation via Alkyne-Directed Remote C-H Arylation and Subsequent Arene Dearomatization>, Formula: C7H7BrO2, the main research area is alkynyl iodobenzene bromophenol palladium catalyst tandem regioselective spiroannulation; C−H activation; aryl halides; cross-coupling; dearomatization; palladacycles.
A highly chemoselective Pd0-catalyzed alkyne-directed cross-coupling of aryl iodides with bromophenols, which was subsequently followed by phenol dearomatization was reported to furnish a very attractive [2+2+1] spiroannulated products. Notably, possible homo-coupling of aryl iodides was not observed at all. Mechanistic studies indicated that a five-membered aryl/vinyl palladacycle most likely accounts for promoting the key step of biaryl cross-coupling.
Angewandte Chemie, International Edition published new progress about Alkynes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 135999-16-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H7BrO2, Formula: C7H7BrO2.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary